2250019-92-0
2250019-92-0
Chemical Structure
Kira8 Hydrochloride
Synonym(s): AMG-18 Hydrochloride
- CAS No.: 2250019-92-0
- Formula:C31H30Cl2N6O3S
- Molecular Weight:637.58
IUPAC Name: (R)-2-chloro-N-(6-methyl-5-((3-(2-(piperidin-3-ylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-yl)benzenesulfonamide hydrochloride
InChIKey: CNWIPRHGMZTPSB-ZMBIFBSDSA-N
SMILES: O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(C3=CC=C2)OC4=NC=CC=C4C5=NC(N[C@H]6CNCCC6)=NC=C5)=O.[H]Cl
Biological Activity: Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kira8 Hydrochloride | 98.03% | Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. | ||||||||||||||||||||
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