2251709-91-6
2251709-91-6
Chemical Structure
PLK1/BRD4-IN-3
- CAS No.: 2251709-91-6
- Formula:C31H43N7O3
- Molecular Weight:561.72
InChIKey: HTPNGOWITIWAHM-FQEVSTJZSA-N
SMILES: O=C1[C@H](C)N(C2CCCC2)C3=NC(NC4=CC=C(C(NC5CCN(C)CC5)=O)C=C4OC6CCCC6)=NC=C3N1C
Biological Activity: PLK1/BRD4-IN-3 (Compound 21) is a selective dual inhibitor for bromodomain 4 (BRD4) and polo-like kinase 1 (PLK1). PLK1/BRD4-IN-3 inhibits BRD4-BD1, PLK1 and BRDT-BD1, with IC50s of 0.059, 0.127 and 0.245 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PLK1/BRD4-IN-3 | 98.55% | PLK1/BRD4-IN-3 (Compound 21) is a selective dual inhibitor for bromodomain 4 (BRD4) and polo-like kinase 1 (PLK1). PLK1/BRD4-IN-3 inhibits BRD4-BD1, PLK1 and BRDT-BD1, with IC50s of 0.059, 0.127 and 0.245 μM, respectively. | ||||||||||||||||||||
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References
Keywords
