2252446-26-5
2252446-26-5
Chemical Structure
LSD1-UM-109
- CAS No.: 2252446-26-5
- Formula:C29H27FN6
- Molecular Weight:478.56
InChIKey: PFIZMWHCYFWQEI-UHFFFAOYSA-N
SMILES: CN(N=C1)C2=C1C=C(C=C2)C3=C(C4=CC=C(C#N)C(F)=C4)C5=C(N(CC6(C)CCNCC6)C=C5)C=N3
Biological Activity: LSD1-UM-109 is a ighly potent and reversible LSD1 inhibitor with an IC50 of 3.1 nM. LSD1-UM-109 inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line[1].
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LSD1-UM-109 | LSD1-UM-109 is a ighly potent and reversible LSD1 inhibitor with an IC50 of 3.1 nM. LSD1-UM-109 inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line. | |||||||||||||||||||||
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References
Keywords
