2259620-80-7
2259620-80-7
Chemical Structure
PDE12-IN-1
- CAS No.: 2259620-80-7
- Formula:C31H27BrFN5O3
- Molecular Weight:616.48
IUPAC Name: 3-(5-bromo-6-((2R,3R)-2-(4-fluorophenyl)-3-(hydroxymethyl)morpholine-4-carbonyl)-1-methyl-1H-benzo[d]imidazol-2-yl)-1-ethyl-1H-indole-6-carbonitrile
InChIKey: YWMAQKQMUXYMAZ-FQLXRVMXSA-N
SMILES: N#CC1=CC2=C(C=C1)C(C3=NC4=CC(Br)=C(C(N5[C@H](CO)[C@@H](C6=CC=C(F)C=C6)OCC5)=O)C=C4N3C)=CN2CC
Biological Activity: PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2′,5′-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PDE12-IN-1 | 99.11% | PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2′,5′-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity. | ||||||||||||||||||||
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