226566-43-4
226566-43-4
Chemical Structure
RWJ-445167
Synonym(s): 3DP-10017
- CAS No.: 226566-43-4
- Formula:C18H24N6O5S
- Molecular Weight:436.49
IUPAC Name: N-(2-(guanidinooxy)ethyl)-2-(6-methyl-3-((3-methylphenyl)sulfonamido)-2-oxopyridin-1(2H)-yl)acetamide
InChIKey: GHCPCZIUEYRYJT-UHFFFAOYSA-N
SMILES: O=C(NCCONC(N)=N)CN1C(C)=CC=C(NS(=O)(C2=CC=CC(C)=C2)=O)C1=O
Biological Activity: RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.
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RWJ-445167 | RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. | |||||||||||||||||||||
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Keywords
