1. Metabolic Enzyme/Protease
  2. Thrombin
    Factor Xa
  3. RWJ-445167

RWJ-445167 (Synonyms: 3DP-10017)

Cat. No.: HY-19373
Handling Instructions

RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

For research use only. We do not sell to patients.

RWJ-445167 Chemical Structure

RWJ-445167 Chemical Structure

CAS No. : 226566-43-4

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Description

RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

IC50 & Target

Ki: 4.0 nM (thrombin), 230 nM (factor Xa)[1]

Molecular Weight

436.49

Formula

C₁₈H₂₄N₆O₅S

CAS No.

226566-43-4

SMILES

O=C(NCCONC(N)=N)CN1C(C)=CC=C(NS(=O)(C2=CC=CC(C)=C2)=O)C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

RWJ-4451673DP-10017RWJ445167RWJ 445167ThrombinFactor XaFxadualinhibitorantithromboticactivityInhibitorinhibit

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RWJ-445167
Cat. No.:
HY-19373
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