226717-28-8
226717-28-8
Chemical Structure
AGL 2043
- CAS. Nr.: 226717-28-8
- Formula:C15H12N4S
- Molecular Weight:280.35
IUPAC Name: 1,2-dimethyl-6-(thiophen-2-yl)-1H-imidazo[4,5-g]quinoxaline
InChIKey: ZGDACLBJJXLKJY-UHFFFAOYSA-N
SMILES: CC(N1C)=NC2=C1C=C3N=CC(C4=CC=CS4)=NC3=C2
Biological Activity: AGL 2043 is an effective inhibitor of PDGFR (IC50=0.8 μM) and TEL-PDGFR kinases, as well as FLT3 and KIT kinases. AGL 2043 can effectively inhibit porcine cardiac smooth muscle cell proliferation and balloon-induced vascular stenosis, and is suitable for development as an anti-restenotic and anticancer agent[1].
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AGL 2043 | AGL 2043 is an effective inhibitor of PDGFR (IC50=0.8 μM) and TEL-PDGFR kinases, as well as FLT3 and KIT kinases. AGL 2043 can effectively inhibit porcine cardiac smooth muscle cell proliferation and balloon-induced vascular stenosis, and is suitable for development as an anti-restenotic and anticancer agent. | |||||||||||||||||||||
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