226975-99-1
Chemical Structure
Hyponine E
Synonym(s): (-)-Hyponine E
- CAS No.: 226975-99-1
- Formula:C45H48N2O19
- Molecular Weight:920.86
IUPAC Name: (52R,53R,54R,55S,55aR,56R,57R,58S,59S,59aS,510R)-55a-(acetoxymethyl)-510-((furan-2-carbonyl)oxy)-59-hydroxy-52,59,8,9-tetramethyl-54-(nicotinoyloxy)-2,7-dioxo-53,54,55,55a,56,57,58,59-octahydro-52H-3,6-dioxa-1(3,2)-pyridina-5(2,8)-3,9a-methanobenzo[b]oxep
InChIKey: PMRSIAJYXABCTQ-IWYQQVOHSA-N
SMILES: CC1C(C)C(O[C@H]2[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@]3(COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C4=CN=CC=C4)=O)[C@@H]5[C@@H](OC(C6=CC=CO6)=O)[C@]3(O[C@@]5(C)COC(C7=C1N=CC=C7)=O)[C@]2(O)C)=O
Biological Activity: Hyponine E, a macrocyclic sesquiterpene pyridine alkaloid that could be isolated from from Tripterygium hypoglaucum, possesses anti-inflammatory effects[1][2].
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Hyponine E | Hyponine E, a macrocyclic sesquiterpene pyridine alkaloid that could be isolated from from Tripterygium hypoglaucum, possesses anti-inflammatory effects. | |||||||||||||||||||||
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- [1]. HongquanDuan, et al. Sesquiterpene evoninate alkaloids from Tripterygium hypoglaucum. Phytochemistry Volume 52, Issue 8, December 1999, Pages 1735-1738.
- [2]. Mei Xue, et al. Anti-inflammatory effects and hepatotoxicity of Tripterygium-loaded solid lipid nanoparticles on adjuvant-induced arthritis in rats. Phytomedicine. 2012 Aug 15;19(11):998-1006. [Content Brief]
Keywords
