2290562-59-1
2290562-59-1
Chemical Structure
Exatecan intermediate 9
- CAS No.: 2290562-59-1
- Formula:C26H24FN3O5
- Molecular Weight:477.48
IUPAC Name: N-((9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)acetamide
InChIKey: SRCUCWPOTBGIQM-IHZSNKTASA-N
SMILES: O=C(OC1)[C@](O)(CC)C2=C1C(N3C(C4=NC5=CC(F)=C(C)C6=C5C(C(NC(C)=O)CC6)=C4C3)=C2)=O
Biological Activity: Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].
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Exatecan intermediate 9 | Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM). | |||||||||||||||||||||
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