2320262-09-5
Chemical Structure
RUSKI-201 dihydrochloride
- CAS No.: 2320262-09-5
- Formula:C20H29Cl2N3OS
- Molecular Weight:430.43
IUPAC Name: 2-((2-methylbutyl)amino)-1-(4-(6-methylpyridin-2-yl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethan-1-one dihydrochloride
InChIKey: TUDOZEOETHEGCR-UHFFFAOYSA-N
SMILES: CCC(CNCC(N1CCC2=C(C1C3=NC(C)=CC=C3)C=CS2)=O)C.Cl.Cl
Biological Activity: RUSKI-201 dihydrochloride is a potent and specific Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 0.20 μM. RUSKI-201 dihydrochloride is able to block Hh signaling from Shh overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is potential Hhat chemical probe in cells and can used in studies of Hhat catalytic function[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RUSKI-201 dihydrochloride | 98.2% | RUSKI-201 dihydrochloride is a potent and specific Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 0.20 μM. RUSKI-201 dihydrochloride is able to block Hh signaling from Shh overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is potential Hhat chemical probe in cells and can used in studies of Hhat catalytic function. | ||||||||||||||||||||
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Keywords
