2347368-51-6
2347368-51-6
Chemical Structure
JNJ-7184
- CAS No.: 2347368-51-6
- Formula:C30H27FN4O3
- Molecular Weight:510.56
InChIKey: MBPRXFPDWJSDRO-AVIJNYRZSA-N
SMILES: C[C@H]1N(C(C2=NC3=CC(C4=CC=C([C@@H]5[C@@H](C(O)=O)C5)C=C4F)=NN3C(C6CC6)=C2)=O)CCC7=CC=CC=C71
Biological Activity: JNJ-7184 is a non-nucleoside inhibitor of the RSV-Large (L) polymerase, with the pEC50 and pCC50 of 7.86 and 4.29 in Hela cells, respectively. JNJ-7184 prevents RSV replication and transcription by inhibiting initiation or early elongation[1].
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JNJ-7184 | JNJ-7184 is a non-nucleoside inhibitor of the RSV-Large (L) polymerase, with the pEC50 and pCC50 of 7.86 and 4.29 in Hela cells, respectively. JNJ-7184 prevents RSV replication and transcription by inhibiting initiation or early elongation. | |||||||||||||||||||||
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References
Keywords
