2349429-73-6
2349429-73-6
Chemical Structure
(S,R,S)-AHPC-Me-CO-C4-COOH
- CAS No.: 2349429-73-6
- Formula:C29H40N4O6S
- Molecular Weight:572.72
IUPAC Name: 6-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-6-oxohexanoic acid
InChIKey: FAIAMASTJQSIOK-OFCWLIIESA-N
SMILES: C([C@@H](NC(CCCCC(O)=O)=O)[C@@](C)(C)C)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
Biological Activity: (S,R,S)-AHPC-Me-CO-C4-COOH is a conjugate of the E3 ligase VHL ligand and a linker, which can be used to synthesize PROTAC ERα Degrader-12 (HY-174453). PROTAC ERα Degrader-12 is a potent and highly selective ERα PROTAC degrader[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S,R,S)-AHPC-Me-CO-C4-COOH | 99.75% | (S,R,S)-AHPC-Me-CO-C4-COOH is a conjugate of the E3 ligase VHL ligand and a linker, which can be used to synthesize PROTAC ERα Degrader-12 (HY-174453). PROTAC ERα Degrader-12 is a potent and highly selective ERα PROTAC degrader. | ||||||||||||||||||||
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