2374772-60-6
2374772-60-6
Chemical Structure
J-1048
- CAS No.: 2374772-60-6
- Formula:C23H17FN6S2
- Molecular Weight:460.55
InChIKey: TVWMUKRZUMLJMU-UHFFFAOYSA-N
SMILES: FC1=CC(NC(CN2C=C(C3=CC4=NSN=C4C=C3)C(C5=CC=CC(C)=N5)=N2)=S)=CC=C1
Biological Activity: J-1048 is an activin receptor-like kinase 5 (ALK5) inhibitor. J-1048 can inhibit TAA-induced liver fibrosis in mice by explicitly blocking the TGF-β/Smad signaling pathway[1].
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J-1048 | J-1048 is an activin receptor-like kinase 5 (ALK5) inhibitor. J-1048 can inhibit TAA-induced liver fibrosis in mice by explicitly blocking the TGF-β/Smad signaling pathway. | |||||||||||||||||||||
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