2376990-26-8
Chemical Structure
(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride
Synonym(s): VH032-phenol-C4-NH2 dihydrochloride
- CAS No.: 2376990-26-8
- Formula:C28H43Cl2N5O5S
- Molecular Weight:632.64
IUPAC Name: (2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-N-(2-(4-aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
InChIKey: LDWASNPVOMODPJ-OTCWRJAQSA-N
SMILES: [H]Cl.[H]Cl.CC(N[C@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2OCCCCN)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C)=O
Biological Activity: (S,R,S)-AHPC-phenol-C4-NH2 (VH032-phenol-C4-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology[1].
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(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride | (S,R,S)-AHPC-phenol-C4-NH2 (VH032-phenol-C4-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology. | |||||||||||||||||||||
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