2379577-82-7
2379577-82-7
Chemical Structure
WSF1-IN-1
- CAS No.: 2379577-82-7
- Formula:C20H21F3N8O
- Molecular Weight:446.43
IUPAC Name: (S)-4,7,8-trimethyl-2-(((1-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-pyrazol-4-yl)methyl)amino)-7,8-dihydropteridin-6(5H)-one
InChIKey: KKHCZENFFDIZHM-LBPRGKRZSA-N
SMILES: CN([C@H]1C)C2=NC(NCC(C=N3)=CN3CC(C=C4)=CN=C4C(F)(F)F)=NC(C)=C2NC1=O
Biological Activity: WSF1-IN-1 (compound 136), an orally active WSF1 inhibitor, can be used in the study for WSF1 (Wolfram syndrome) related tumors, with IC50 values of 0.33 μM and >27 μM in HepG2 parental and HepG2 WFS1 KO cell lines, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WSF1-IN-1 | 99.91% | WSF1-IN-1 (compound 136), an orally active WSF1 inhibitor, can be used in the study for WSF1 (Wolfram syndrome) related tumors, with IC50 values of 0.33 μM and >27 μM in HepG2 parental and HepG2 WFS1 KO cell lines, respectively. | ||||||||||||||||||||
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References
Keywords
