2380991-16-0
2380991-16-0
Chemical Structure
Monomethyl auristatin E intermediate-16
- CAS No.: 2380991-16-0
- Formula:C20H29NO5
- Molecular Weight:363.45
IUPAC Name: tert-butyl (R)-2-((1S,2S)-3-(benzyloxy)-1-hydroxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
InChIKey: IJTMTCBOXNAACY-UAGQMJEPSA-N
SMILES: O[C@@H]([C@H](C)C(OCC1=CC=CC=C1)=O)[C@@H]2N(C(OC(C)(C)C)=O)CCC2
Biological Activity: Monomethyl auristatin E intermediate-16 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-16 | Monomethyl auristatin E intermediate-16 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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