2382942-31-4
Chemical Structure
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine
- CAS No.: 2382942-31-4
- Formula:C51H69N5O8
- Molecular Weight:880.12
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
InChIKey: PJMOFQPOUATKHV-WBGRFHBGSA-N
SMILES: O[C@H]1[C@@H](OCCCCCCCCCCCCCCCC)[C@H](N(C=N2)C3=C2C(NC(NC(C(C)C)=O)=N3)=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Biological Activity: N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine | N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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