2402790-58-1
2402790-58-1
Chemical Structure
Thalidomide-O-amido-PEG3-azide
- CAS No.: 2402790-58-1
- Formula:C23H28N6O9
- Molecular Weight:532.51
IUPAC Name: N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
InChIKey: LPOYGZDPGIZIFJ-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCOCCOCCOCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Biological Activity: Thalidomide-O-amido-PEG3-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-amido-PEG3-azide can be linked to a target protein ligand via a linker to form a PROTAC.
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Thalidomide-O-amido-PEG3-azide | Thalidomide-O-amido-PEG3-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-amido-PEG3-azide can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
