2409544-80-3
Chemical Structure
TRK-IN-17
- CAS No.: 2409544-80-3
- Formula:C21H21F2N7S
- Molecular Weight:441.50
IUPAC Name: (Z)-N'-cyano-N-ethyl-6-((2R,4S)-4-fluoro-2-(3-fluoro-5-(methylthio)phenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazine-3-carboximidamide
InChIKey: XSAZBCHAGYBUBI-DOTOQJQBSA-N
SMILES: CCN/C(C1=CN=C2C=CC(N3C[C@H](C[C@@H]3C4=CC(F)=CC(SC)=C4)F)=NN12)=N\C#N
Biological Activity: TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3)[1].
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TRK-IN-17 | TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3). | |||||||||||||||||||||
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Keywords
