2411741-01-8
Chemical Structure
Antituberculosis agent-2
- CAS No.: 2411741-01-8
- Formula:C19H17NO4
- Molecular Weight:323.34
IUPAC Name: 5-(azetidin-1-ylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
InChIKey: YONQTMXRNDKBLV-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=C(O)C=C2)OC3=CC=C(O)C(CN4CCC4)=C13
Biological Activity: Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against agent-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 μg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability[1].
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Antituberculosis agent-2 | Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against agent-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 μg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability. | |||||||||||||||||||||
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Keywords
