2415330-04-8
2415330-04-8
Chemical Structure
Zorevunersen
Synonym(s): STK-001
- CAS No.: 2415330-04-8
- Formula:C204H263N63O114P20S20
- Molecular Weight:7197.20
SMILES: [Zorevunersen]
Biological Activity: Zorevunersen is an antisense oligonucleotide targeting the Scn1a gene based on TANGO technology. Zorevunersen increases Scn1a mRNA transcripts and elevates the expression level of NaV1.1 protein. Zorevunersen restores the excitability of PV interneurons, thereby reducing seizures and prolonging survival in mice. Zorevunersen can be used for research on Dravet syndrome[1].
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Zorevunersen | 98.50% | Zorevunersen is an antisense oligonucleotide targeting the Scn1a gene based on TANGO technology. Zorevunersen increases Scn1a mRNA transcripts and elevates the expression level of NaV1.1 protein. Zorevunersen restores the excitability of PV interneurons, thereby reducing seizures and prolonging survival in mice. Zorevunersen can be used for research on Dravet syndrome. | ||||||||||||||||||||
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References
Keywords
