2416021-47-9
Chemical Structure
DDR1-IN-6
- CAS No.: 2416021-47-9
- Formula:C23H14F3N5O
- Molecular Weight:433.39
IUPAC Name: 7-(imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-(3-(trifluoromethyl)phenyl)benzo[d]isoxazol-3-amine
InChIKey: GDBAAUWGHRTFSE-UHFFFAOYSA-N
SMILES: FC(C1=CC(NC2=NOC3=C2C=CC(C)=C3C#CC4=CN=C5C=CC=NN54)=CC=C1)(F)F
Biological Activity: DDR1-IN-6 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 9.72 nM. DDR1-IN-6 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 9.7 nM. DDR1-IN-6 has anti-cancer activity[1]. DDR1-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DDR1-IN-6 | 98.02% | DDR1-IN-6 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 9.72 nM. DDR1-IN-6 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 9.7 nM. DDR1-IN-6 has anti-cancer activity. DDR1-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords