2416400-32-1
Chemical Structure
DNA Gyrase-IN-4
- CAS No.: 2416400-32-1
- Formula:C22H15Cl2NO4S
- Molecular Weight:460.33
IUPAC Name: (4-chlorophenyl)(4,5-dimethylthiazol-2-yl)methyl 6-chloro-2-oxo-2H-chromene-3-carboxylate
InChIKey: YMHLFZHIJKICAJ-UHFFFAOYSA-N
SMILES: O=C(C(C1=O)=CC2=C(O1)C=CC(Cl)=C2)OC(C3=CC=C(Cl)C=C3)C4=NC(C)=C(C)S4
Biological Activity: DNA Gyrase-IN-4 (compound 8p) is a potent DNA gyrase inhibitor, with an IC50 of 0.13 μM. DNA Gyrase-IN-4 shows excellent antibacterial activity against Staphylococcus aureus, Listeria monocytogenes, Salmonella and Escherichia coli, with MIC values of 0.05, 0.05, 0.05, and 8 μg/mL, respectively[1].
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DNA Gyrase-IN-4 | DNA Gyrase-IN-4 (compound 8p) is a potent DNA gyrase inhibitor, with an IC50 of 0.13 μM. DNA Gyrase-IN-4 shows excellent antibacterial activity against Staphylococcus aureus, Listeria monocytogenes, Salmonella and Escherichia coli, with MIC values of 0.05, 0.05, 0.05, and 8 μg/mL, respectively. | |||||||||||||||||||||
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