2417096-44-5
Chemical Structure
RuBi-Glutamate hexafluorophosphate sodium
- CAS No.: 2417096-44-5
- Formula:C28H32F12N5Na2O4P3Ru
- Molecular Weight:970.54
InChIKey: SQQVSHWHIPVYSZ-BRAOKRETSA-L
SMILES: [F-][P+5]([F-])([F-])([F-])([F-])[F-].O=C(O[Na])[C@H](CCC(O[Na])=O)[NH2][Ru+2]12([N]3=CC=CC=C3C4=CC=CC=[N]14)([N]5=CC=CC=C5C6=CC=CC=[N]26)[P](C)(C)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
Biological Activity: RuBi-Glutamate hexafluorophosphate sodium is a neuronal activator. RuBi-Glutamate hexafluorophosphate sodium photocleaves to release glutamate upon one- or two-photon excitation, activating glutamate receptors in cortical pyramidal neurons. RuBi-Glutamate hexafluorophosphate sodium reduces peak amplitude of evoked GABAergic inhibitory postsynaptic currents in its caged form. RuBi-Glutamate hexafluorophosphate sodium can be used for the research of Huntington's disease[1][2].
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RuBi-Glutamate hexafluorophosphate sodium | 82.94% | RuBi-Glutamate hexafluorophosphate sodium is a neuronal activator. RuBi-Glutamate hexafluorophosphate sodium photocleaves to release glutamate upon one- or two-photon excitation, activating glutamate receptors in cortical pyramidal neurons. RuBi-Glutamate hexafluorophosphate sodium reduces peak amplitude of evoked GABAergic inhibitory postsynaptic currents in its caged form. RuBi-Glutamate hexafluorophosphate sodium can be used for the research of Huntington's disease. | ||||||||||||||||||||
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- [1]. Fino E, et al. RuBi-Glutamate: Two-Photon and Visible-Light Photoactivation of Neurons and Dendritic spines. Front Neural Circuits. 2009;3:2. Published 2009 May 27. [Content Brief]
- [2]. Dvorzhak A, et al. Functional Indicators of Glutamate Transport in Single Striatal Astrocytes and the Influence of Kir4.1 in Normal and Huntington Mice. J Neurosci. 2016;36(18):4959-4975. [Content Brief]
