2428401-23-2
2428401-23-2
Chemical Structure
PB830
- No. CAS: 2428401-23-2
- Formula:C20H20FN3O
- Molecular Weight:337.39
IUPAC Name: (3-(3-fluorobenzyl)azetidin-1-yl)(5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methanone
InChIKey: GOEJHYPOORTKTG-UHFFFAOYSA-N
SMILES: O=C(N1CC(C1)CC2=CC(F)=CC=C2)N3N=CCC3C4=CC=CC=C4
Biological Activity: PB830 (compound 41) is a potent receptor interacting protein 1 kinase (RIP1) Inhibitor with an IC50 of <100 nM for human RIP1. PB830 has an EC50 of 1-100 nM in the cell necrosis assay[1].
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PB830 | PB830 (compound 41) is a potent receptor interacting protein 1 kinase (RIP1) Inhibitor with an IC50 of <100 nM for human RIP1. PB830 has an EC50 of 1-100 nM in the cell necrosis assay. | |||||||||||||||||||||
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