2428738-43-4
Chemical Structure
CVM-05-002
- CAS No.: 2428738-43-4
- Formula:C16H14N4O3S2
- Molecular Weight:374.44
IUPAC Name: (Z)-N-(4-(5-((2-imino-4-oxothiazolidin-5-ylidene)methyl)pyridin-3-yl)phenyl)methanesulfonamide
InChIKey: AGHDPPGOJJYURV-AUWJEWJLSA-N
SMILES: CS(NC(C=C1)=CC=C1C2=CN=CC(/C=C3SC(NC\3=O)=N)=C2)(=O)=O
Biological Activity: CVM-05-002 is a selective pan-phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) inhibitor, with IC50 values of 0.27 μM and 1.69 μM against PI5P4Kα and PI5P4Kβ, respectively. CVM-05-002 binds non-covalently to the ATP-binding pocket of PI5P4Kα, forming hydrophobic interactions and hydrogen bonds with pocket residues. CVM-05-002 can be used in tumor-related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CVM-05-002 | 98.83% | CVM-05-002 is a selective pan-phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) inhibitor, with IC50 values of 0.27 μM and 1.69 μM against PI5P4Kα and PI5P4Kβ, respectively. CVM-05-002 binds non-covalently to the ATP-binding pocket of PI5P4Kα, forming hydrophobic interactions and hydrogen bonds with pocket residues. CVM-05-002 can be used in tumor-related research. | ||||||||||||||||||||
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