2428743-04-6
2428743-04-6
Chemical Structure
FGFR3-IN-1
- CAS No.: 2428743-04-6
- Formula:C28H39N9O3S
- Molecular Weight:581.73
IUPAC Name: N-ethyl-2-((4-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-1,3,5-triazin-2-yl)amino)benzenesulfonamide
InChIKey: YJUANBRSJHPDHJ-UHFFFAOYSA-N
SMILES: CCNS(=O)(C1=CC=CC=C1NC2=NC(NC3=CC(OC)=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)=NC=N2)=O
Biological Activity: FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer[1].
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FGFR3-IN-1 | FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer. | |||||||||||||||||||||
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References
Keywords
