2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR3-IN-1

FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer.

For research use only. We do not sell to patients.

FGFR3-IN-1 Chemical Structure

FGFR3-IN-1 Chemical Structure

CAS No. : 2428743-04-6

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FGFR3-IN-1 Related Antibodies

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Description

FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer[1].

IC50 & Target[1]

FGFR1

40 nM (IC50)

FGFR2

5.1 nM (IC50)

FGFR3

12 nM (IC50)

Molecular Weight

581.73

Formula

C28H39N9O3S
CAS No.
SMILES

CCNS(=O)(C1=CC=CC=C1NC2=NC(NC3=CC(OC)=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)=NC=N2)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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FGFR3-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGFR3-IN-12428743-04-6FGFRFibroblast growth factor receptorbladder cancerInhibitorinhibitorinhibit

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