2446376-25-4
2446376-25-4
Chemical Structure
PM534
- CAS No.: 2446376-25-4
- Formula:C20H27N3O5S
- Molecular Weight:421.51
InChIKey: FEAXXOSOWZCDTJ-NVUXMUDASA-N
SMILES: O=C([C@]1(N=C(SC1)/C(C)=N/O)C)N[C@@H](C2=CC(OCC3CC3)=CC(O2)=O)CCC
Biological Activity: PM534, tubulin targeting agent, inhibits tubulin assembly with IC50 values of 0.8-3.2 nM. PM534 binds to the colchicine site of tubulin, which has high antitumor activity[1].
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PM534 | PM534, tubulin targeting agent, inhibits tubulin assembly with IC50 values of 0.8-3.2 nM. PM534 binds to the colchicine site of tubulin, which has high antitumor activity. | |||||||||||||||||||||
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References
Keywords
