2448414-48-8
2448414-48-8
Chemical Structure
BRD7-IN-1
- CAS. Nr.: 2448414-48-8
- Formula:C22H28Cl2N4O3
- Molecular Weight:467.39
IUPAC Name: 4-(3,5-dimethoxy-4-(piperazin-1-ylmethyl)phenyl)-2-methyl-2,7-naphthyridin-1(2H)-one dihydrochloride
InChIKey: VUBFYDKFJHVJDQ-UHFFFAOYSA-N
SMILES: CN1C=C(C2=CC(OC)=C(CN3CCNCC3)C(OC)=C2)C(C=CN=C4)=C4C1=O.Cl.Cl
Biological Activity: BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively)[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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BRD7-IN-1 | 99.77% | BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively). | ||||||||||||||||||||
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References
Keywords
