2459950-15-1
2459950-15-1
Chemical Structure
DNA topoisomerase II inhibitor 1
- CAS No.: 2459950-15-1
- Formula:C28H24N4O3S
- Molecular Weight:496.58
IUPAC Name: (1-phenyl-9H-pyrido[3,4-b]indol-3-yl)(4-(phenylsulfonyl)piperazin-1-yl)methanone
InChIKey: KYJLNQLOFWJHOQ-UHFFFAOYSA-N
SMILES: O=C(N1CCN(S(C2=CC=CC=C2)(=O)=O)CC1)C3=CC4=C(C(C5=CC=CC=C5)=N3)NC6=C4C=CC=C6
Biological Activity: DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase[1].
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DNA topoisomerase II inhibitor 1 | DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase. | |||||||||||||||||||||
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References
Keywords
