2488891-30-9
2488891-30-9
Chemical Structure
PI3K/AKT-IN-3
- CAS No.: 2488891-30-9
- Formula:C44H63N5O7
- Molecular Weight:774.00
InChIKey: ZOMCQRCIHKZDPP-WGKRXOJASA-N
SMILES: COC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C([C@@H](C5)CC6=CN([C@@H]7[C@H](O[C@@H](N8C(NC(C(C)=C8)=O)=O)C7)CO)N=N6)=O)C)([H])CC4)C)([H])CC3)C)C)=O
Biological Activity: PI3K/AKT-IN-3 (compound 8C) can induce autophagy and apoptosis by inhibiting the PI3K/AKT signaling pathway. PI3K/AKT-IN-3 can be used in cancer research[1].
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PI3K/AKT-IN-3 | PI3K/AKT-IN-3 (compound 8C) can induce autophagy and apoptosis by inhibiting the PI3K/AKT signaling pathway. PI3K/AKT-IN-3 can be used in cancer research. | |||||||||||||||||||||
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References
- [1]. Wang Q, Ma F, Wang J, Xu H, Li K, Cheng YY, Chen X, Qu S, Wei T, Hao X, Kong M, Xie C, Wang W, Wang Y, Jeong LS. Antitumor activity and transcriptome sequencing (RNA-seq) analyses of hepatocellular carcinoma cells in response to exposure triterpene-nucleoside conjugates. Eur J Med Chem. 2024 Jun 28;276:116635. [Content Brief]
Keywords
