2490538-46-8

Tubulin polymerization-IN-25 Chemical Structure
2490538-46-8

Chemical Structure

Tubulin polymerization-IN-25

  • CAS No.: 2490538-46-8
  • Formula:C24H18N2O3S
  • Molecular Weight:414.48

IUPAC Name: 1-(7-methoxy-1-(10H-phenothiazine-3-carbonyl)indolizin-3-yl)ethan-1-one

InChIKey: BCMHNIFQYIRJNQ-UHFFFAOYSA-N

SMILES: CC(C1=CC(C(C2=CC=C3NC4=C(C=CC=C4)SC3=C2)=O)=C5C=C(OC)C=CN15)=O

Biological Activity: Tubulin polymerization-IN-25 (compound 17f) is a dual inhibitor of tubulin polymerization and farnesyl transferase (FTase) with IC50s of 1.11 μM and 0.39 μM, respectively. Tubulin polymerization-IN-25 displays cytotoxicity and excellent antitumor activity [1].

Cat. No. Product Name Purity Description Pricing
HY-149016 		Tubulin polymerization-IN-25 Tubulin polymerization-IN-25 (compound 17f) is a dual inhibitor of tubulin polymerization and farnesyl transferase (FTase) with IC50s of 1.11 μM and 0.39 μM, respectively. Tubulin polymerization-IN-25 displays cytotoxicity and excellent antitumor activity .
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