2516246-24-3
Chemical Structure
FtsZ-IN-1
- CAS No.: 2516246-24-3
- Formula:C26H32IN3
- Molecular Weight:513.46
IUPAC Name: (E)-2-(4-(dimethylamino)styryl)-1-methyl-4-(4-methylpiperidin-1-yl)quinolin-1-ium iodide
InChIKey: QNSNMYHREQPTRX-UHFFFAOYSA-M
SMILES: CC1CCN(C2=C3C=CC=CC3=[N+](C)C(/C=C/C4=CC=C(N(C)C)C=C4)=C2)CC1.[I-]
Biological Activity: FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity[1].
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FtsZ-IN-1 | FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity. | |||||||||||||||||||||
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Keywords
