252920-94-8
Chemical Structure
Solabegron
Synonym(s): GW 427353
- CAS No.: 252920-94-8
- Formula:C23H23ClN2O3
- Molecular Weight:410.89
IUPAC Name: (R)-3'-((2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)ethyl)amino)-[1,1'-biphenyl]-3-carboxylic acid
InChIKey: LLDXOPKUNJTIRF-QFIPXVFZSA-N
SMILES: O=C(C1=CC(C2=CC=CC(NCCNC[C@@H](C3=CC=CC(Cl)=C3)O)=C2)=CC=C1)O
Biological Activity: Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM[1]. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Solabegron | 99.89% | Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome. | ||||||||||||||||||||
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Solabegron-d8 | Solabegron-d8 (GW 427353-d8) is deuterium labeled Solabegron. Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome. | |||||||||||||||||||||
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Keywords
