2614335-77-0
2614335-77-0
Chemical Structure
Bz-DTPA hydrochloride
- CAS No.: 2614335-77-0
- Formula:C22H31Cl3N4O10S
- Molecular Weight:649.93
InChIKey: DZDFYEZTPUIJAP-FCQHKQNSSA-N
SMILES: OC(CN(CC(O)=O)[C@H](CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O)CC1=CC=C(C=C1)N=C=S)=O.Cl.Cl.Cl
Biological Activity: Bz-DTPA hydrochloride is a bifunctional chelator that can conjugate indium radionuclides to targeting proteins for tumor-targeted tracing. Bz-DTPA hydrochloride is mainly used in studies related to radioactive targeting molecules[1][2].
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Bz-DTPA hydrochloride | Bz-DTPA hydrochloride is a bifunctional chelator that can conjugate indium radionuclides to targeting proteins for tumor-targeted tracing. Bz-DTPA hydrochloride is mainly used in studies related to radioactive targeting molecules. | |||||||||||||||||||||
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References
- [1]. Tolmachev V, et al. Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice. Cancer biotherapy & radiopharmaceuticals. 2004 Aug;19(4):491-501.
- [2]. Tolmachev V, et al. The influence of Bz‑DOTA and CHX‑A''‑DTPA on the biodistribution of ABD‑fused anti‑HER2 Affibody molecules: implications for 114mIn‑mediated targeting therapy. Eur J Nucl Med Mol Imaging, 2009, 36:1460‑1468.
