26241-51-0
Chemical Structure
Azadiradione
- CAS No.: 26241-51-0
- Formula:C28H34O5
- Molecular Weight:450.57
IUPAC Name: (5R,7R,8R,9R,10R,13S,17R)-17-(furan-3-yl)-4,4,8,10,13-pentamethyl-3,16-dioxo-4,5,6,7,8,9,10,11,12,13,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-7-yl acetate
InChIKey: KWAMDQVQFVBEAU-HMWIRDDCSA-N
SMILES: C[C@]12C([C@]([C@]3([H])C4=COC=C4)(CC[C@]1([H])[C@@]5([C@@](C(C)(C(C=C5)=O)C)([H])C[C@H]2OC(C)=O)C)C)=CC3=O
Biological Activity: Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities[1][2].
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Azadiradione | Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities. | |||||||||||||||||||||
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- [1]. K Ilango, et al. Anti-nociceptive and anti-inflammatory activities of Azadirachta indica fruit skin extract and its isolated constituent azadiradione. Nat Prod Res. 2013;27(16):1463-7. [Content Brief]
- [2]. Brijesh Kumar Singh, et al. Azadiradione Restores Protein Quality Control and Ameliorates the Disease Pathogenesis in a Mouse Model of Huntington's Disease. Mol Neurobiol. 2018 Aug;55(8):6337-6346. [Content Brief]
Keywords
