2634646-14-1
Chemical Structure
EGFR-IN-22
- CAS No.: 2634646-14-1
- Formula:C38H47BrFN10O2P
- Molecular Weight:805.72
IUPAC Name: (6-((5-bromo-2-((4-(9-(1-fluoro-2-methylpropan-2-yl)-3,9-diazaspiro[5.5]undecan-3-yl)-2-methoxy-5-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)pyrimidin-4-yl)amino)quinoxalin-5-yl)dimethylphosphine oxide
InChIKey: FRZRMIPAYIRAHD-UHFFFAOYSA-N
SMILES: O=P(C)(C)C1=C2N=CC=NC2=CC=C1NC3=NC(NC4=C(OC)C=C(N5CCC6(CCN(C(C)(CF)C)CC6)CC5)C(C7=CN(C)N=C7)=C4)=NC=C3Br
Biological Activity: EGFR-IN-22 is a potent EGFR inhibitor with IC50s of 4.91 nM and 0.54 nM for wild type EGFR and EGFRL858R/T790M/C797S, respectively (CN112538072A, compound 243)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR-IN-22 | EGFR-IN-22 is a potent EGFR inhibitor with IC50s of 4.91 nM and 0.54 nM for wild type EGFR and EGFRL858R/T790M/C797S, respectively (CN112538072A, compound 243). | |||||||||||||||||||||
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Keywords
