2636846-37-0
2636846-37-0
Chemical Structure
Rezatapopt analog-1
Synonym(s): PC14586 analog-1
- CAS No.: 2636846-37-0
- Formula:C27H28F4N4O3
- Molecular Weight:532.53
InChIKey: MVRDJZLQYLSZEE-RBBKRZOGSA-N
SMILES: FC(F)(F)CN1C2=CC=CC(N[C@H]3[C@H](CN(CC3)C)F)=C2C=C1C#CCNC4=C(C=C(C=C4)C(O)=O)OC
Biological Activity: Rezatapopt analog-1 (PC14586 analog-1) (1919) is a Rezatapopt (HY-156633) analog. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure[1].
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Rezatapopt analog-1 | Rezatapopt analog-1 (PC14586 analog-1) (1919) is a Rezatapopt (HY-156633) analog. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. | |||||||||||||||||||||
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References
Keywords
