2647371-60-4
2647371-60-4
Chemical Structure
(R)-Zadavotide guraxetan
Synonym(s): (R)-PSMA I&T;(R)-PNT-2002
- CAS No.: 2647371-60-4
- Formula:C63H92IN11O23
- Molecular Weight:1498.37
SMILES: O=C(CC[C@@H](N1CCN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CC(O)=O)C(O)=O)N[C@H](CC2=CC(I)=C(O)C=C2)C(N[C@H](CC3=CC=CC=C3)C(N[C@H](CCCCNC(CCCCCCC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)C(O)=O)=O)=O
Biological Activity: Zadavotide guraxetan (PSMA I&T; PNT-2002) is a prostate-specific membrane antigen (PSMA) inhibitor. Zadavotide guraxetan has antitumor activity and can be used in prostate cancer-targeted research[1][2].
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(R)-Zadavotide guraxetan | Zadavotide guraxetan (PSMA I&T; PNT-2002) is a prostate-specific membrane antigen (PSMA) inhibitor. Zadavotide guraxetan has antitumor activity and can be used in prostate cancer-targeted research. | |||||||||||||||||||||
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References
- [1]. WHO. International Nonproprietary Names for Pharmaceutical Substances (INN), Proposed International Nonproprietary Names: List 132. WHO Drug Information, Vol. 38 , No. 4, 2024.
- [2]. Weineisen M, et al. 68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies. J Nucl Med. 2015 Aug;56(8):1169-76. [Content Brief]
