2648723-43-5
Chemical Structure
DGKα-IN-4
- CAS No.: 2648723-43-5
- Formula:C30H29N5O4
- Molecular Weight:523.58
InChIKey: NASLVCVITKSRNY-UHFFFAOYSA-N
SMILES: N#CC1=CC2=C(N(C)C(C(C#N)=C2N3CCC(C)(CC3)C4=NC5=C(O4)C=CC(C)=C5)=O)C=C1OC6COCC6
Biological Activity: DGKα-IN-4 (example 432) is a DGKα inhibitor with the IC50 of 0.1 nM, extracted from patent WO2021105117. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-3 has the potential for cancer and immunology study.
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DGKα-IN-4 | DGKα-IN-4 (example 432) is a DGKα inhibitor with the IC50 of 0.1 nM, extracted from patent WO2021105117. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-3 has the potential for cancer and immunology study. | |||||||||||||||||||||
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Keywords