DGKα-IN-4
DGKα-IN-4 (example 432) is a DGKα inhibitor with the IC50 of 0.1 nM, extracted from patent WO2021105117. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-3 has the potential for cancer and immunology study.
For research use only. We do not sell to patients.
- CAS No.: 2648723-43-5
- Formula: C30H29N5O4
- Molecular Weight:523.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
0.1 nM (DGKα)
Chemical Information
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CAS No. 2648723-43-5
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Molecular Weight 523.58
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Formula C30H29N5O4
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SMILES
N#CC1=CC2=C(N(C)C(C(C#N)=C2N3CCC(C)(CC3)C4=NC5=C(O4)C=CC(C)=C5)=O)C=C1OC6COCC6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)