2653338-57-7
2653338-57-7
Chemical Structure
Thalidomide-4-O-C10-Br
- CAS No.: 2653338-57-7
- Formula:C23H29BrN2O5
- Molecular Weight:493.39
InChIKey: QGORDVNYYPGVNP-UHFFFAOYSA-N
SMILES: O=C(C(CC1)N(C2=O)C(C(C2=CC=C3)=C3OCCCCCCCCCCBr)=O)NC1=O
Biological Activity: Thalidomide-4-O-C10-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C10-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-22 (HY-181323)[1].
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Thalidomide-4-O-C10-Br | Thalidomide-4-O-C10-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C10-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-22 (HY-181323). | |||||||||||||||||||||
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References
Keywords
