2653338-58-8
2653338-58-8
Chemical Structure
Thalidomide-4-O-C11-Br
- CAS No.: 2653338-58-8
- Formula:C24H31BrN2O5
- Molecular Weight:507.42
InChIKey: YFICPLZHFHFCTE-UHFFFAOYSA-N
SMILES: O=C(C(CC1)N(C2=O)C(C(C2=CC=C3)=C3OCCCCCCCCCCCBr)=O)NC1=O
Biological Activity: Thalidomide-4-O-C11-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C11-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-23 (HY-181324)[1].
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Thalidomide-4-O-C11-Br | Thalidomide-4-O-C11-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C11-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-23 (HY-181324). | |||||||||||||||||||||
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References
Keywords
