2696409-13-7
2696409-13-7
Chemical Structure
K-757
- CAS No.: 2696409-13-7
- Formula:C32H48NO4P
- Molecular Weight:541.70
IUPAC Name: ((S)-3-cyclopropyl-3-(3-((1-(2-(4,4-dimethylpentyl)-5-methoxyphenyl)piperidin-4-yl)methoxy)phenyl)propyl)phosphinic acid
InChIKey: NVWFVRPJBUNBHL-PMERELPUSA-N
SMILES: COC1=CC=C(CCCC(C)(C)C)C(N2CCC(COC3=CC=CC([C@H](C4CC4)CP(O)(C)=O)=C3)CC2)=C1
Biological Activity: K-757 is a GPR40 agonist with an EC50 of 2.1 ± 0.2 nM for human GPR40. K-757 exhibits a half-life of 1-11 h in Preclinical Species. K-757 stimulates GLP-1 secretion and has potential applications in bariatric research[1].
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K-757 | K-757 is a GPR40 agonist with an EC50 of 2.1 ± 0.2 nM for human GPR40. K-757 exhibits a half-life of 1-11 h in Preclinical Species. K-757 stimulates GLP-1 secretion and has potential applications in bariatric research. | |||||||||||||||||||||
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References
Keywords
