2700896-78-0
Chemical Structure
BChE-IN-14
- CAS No.: 2700896-78-0
- Formula:C24H29N
- Molecular Weight:331.49
IUPAC Name: N-(naphthalen-2-ylmethyl)-N-(3-phenylpropyl)butan-1-amine
InChIKey: NAKYNKMYONGAHY-UHFFFAOYSA-N
SMILES: CCCCN(CC1=CC=C2C=CC=CC2=C1)CCCC3=CC=CC=C3
Biological Activity: BChE-IN-14 (compound 19c) is a selective butyrylcholinesterase (BChE) inhibitor with IC50s of 0.23 and 0.011 μM for eqBChE and hBChE, respectively. BChE-IN-14 shows good blood brain barrier permeation and primary cell safety. BChE-IN-14 is able to restore cognitive impairment in vivo, it can be used for the research of Alzheimer’s disease[1].
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BChE-IN-14 | BChE-IN-14 (compound 19c) is a selective butyrylcholinesterase (BChE) inhibitor with IC50s of 0.23 and 0.011 μM for eqBChE and hBChE, respectively. BChE-IN-14 shows good blood brain barrier permeation and primary cell safety. BChE-IN-14 is able to restore cognitive impairment in vivo, it can be used for the research of Alzheimer’s disease. | |||||||||||||||||||||
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Keywords
