2742982-16-5
Chemical Structure
4-Hydroxy-2-methylbenzenesulfonic acid ammonium
- CAS No.: 2742982-16-5
- Formula:C7H11NO4S
- Molecular Weight:205.23
IUPAC Name: 4-hydroxy-2-methylbenzenesulfonic acid, ammonia salt
InChIKey: TUYNXTXPNQDMFB-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(O)C=C1C)(O)=O.N
Biological Activity: 4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].
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4-Hydroxy-2-methylbenzenesulfonic acid ammonium | 4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability. | |||||||||||||||||||||
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