2757424-54-5
2757424-54-5
Chemical Structure
AR antagonist 14
- CAS No.: 2757424-54-5
- Formula:C22H22ClIN2O2
- Molecular Weight:508.78
InChIKey: LJATYFYKWXQNLZ-MXVIHJGJSA-N
SMILES: ClC1=CC(O[C@H]2C(C)(C)[C@H](NC(C3=CC=C(I)C=C3)=O)C2(C)C)=CC=C1C#N
Biological Activity: AR antagonist 14 is is a PROTAC target protein ligand (Ligands for Target Protein for PROTAC). AR antagonist 14 can be combined with VH 101-amide-piperidine-Pip-alkyne (HY-172625) to synthesize PROTAC degraders (ARD-69 (HY-114402))[1].
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AR antagonist 14 | AR antagonist 14 is is a PROTAC target protein ligand (Ligands for Target Protein for PROTAC). AR antagonist 14 can be combined with VH 101-amide-piperidine-Pip-alkyne (HY-172625) to synthesize PROTAC degraders (ARD-69 (HY-114402)). | |||||||||||||||||||||
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References
Keywords
