2757469-20-6
2757469-20-6
Chemical Structure
Immuno modulator-1
- CAS No.: 2757469-20-6
- Formula:C32H31FN6O4
- Molecular Weight:582.62
InChIKey: XRTHZYGRLVDMEO-HRFSGMKKSA-N
SMILES: C[C@@H](N1CCN(C2=C(C=C(C=N2)C#N)F)CC1)C(C=C3)=CC=C3COC4=C5C(C(N([C@@H]6C(NC(CC6)=O)=O)C5)=O)=CC=C4
Biological Activity: Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM[1].
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Immuno modulator-1 | Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM. | |||||||||||||||||||||
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References
Keywords
