2758114-60-0
2758114-60-0
Chemical Structure
Tubulin polymerization-IN-61
- CAS No.: 2758114-60-0
- Formula:C22H21N3O5
- Molecular Weight:407.42
InChIKey: IWDPVPZMBTZRQM-UHFFFAOYSA-N
SMILES: OC1=CC(C2=CC=C3N=NN(C4=CC(OC)=C(OC)C(OC)=C4)C3=C2)=CC=C1OC
Biological Activity: Tubulin polymerization-IN-61 (Compound 9a) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-61 destroys the microtubule skeleton, blocks the cell cycle in G2/M phase, induces Apoptosis, and inhibits cancer cell migration and colony formation. Tubulin polymerization-IN-61 shows antitumor activity in vivo against 4T1 xenograft model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Tubulin polymerization-IN-61 | Tubulin polymerization-IN-61 (Compound 9a) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-61 destroys the microtubule skeleton, blocks the cell cycle in G2/M phase, induces Apoptosis, and inhibits cancer cell migration and colony formation. Tubulin polymerization-IN-61 shows antitumor activity in vivo against 4T1 xenograft model. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
